Cannabis and Anti-Cancer Mechanisms: A Century-Long Journey While the use of cannabis for medicinal purposes dates back millennia, the 20th century saw a dramatic shift in its legal status and scientific exploration. With the advent of prohibition in the early 1900s, research on cannabis, including its potential anti-cancer effects, faced significant limitations. However, despite these obstacles, a handful of studies throughout the century laid the groundwork for the current wave of research and clinical trials. Early Studies (1900-1960): The first evidence of cannabis's potential anti-tumor activity can be traced back to the early 20th century. In 1911, a study conducted by Dr. W.A. Puckey observed the ability of cannabinoids to inhibit the growth of tumors in mice. In the 1940s, Dr. Raphael Mechoulam, a pioneer in cannabis research, identified cannabidiol (CBD) and tetrahydrocannabinol (THC), the two main cannabinoids responsible for cannabis's therapeutic effects. Subs...
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